As men age, their testosterone levels gradually decrease. This may cause a reduction in lean body mass, an increase in fat, and other undesirable changes. Do testosterone supplements reverse some of these effects? A study in the Netherland assigned 237 men aged 60 to 80 with low or low-normal testosterone levels to either a testosterone supplement or a placebo. The report in the Journal of the American Medical Association described the study as a “double-blind, randomized, placebo-controlled trial.” How would you explain each of these terms to someone who knows no statistics? Select the correct meaning of the term “double-blind”. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to the subject. Double-blind means that the subjects and those responsible for assessing the effectiveness of the treatment were not known to each other. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to both the subject and those responsible for assessing the effectiveness of that treatment. Double-blind means that the treatment-testosterone or placebo-assigned to a subject was unknown to those responsible for assessing the effectiveness of that treatment.
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